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药用蛋白的PEG修饰方法-NH2-PEG-OH(NHS/MAL/COOH/CHO/FITC)
1.修饰反应器设计—PEG-pellet 反应器
 
创新技术（反应器技术和产物移走技术）
产品：
Acrylates-peg-Acrylates
Lipoicacid-peg-Acrylates
Tosylate-peg-Acrylates
Aminooxy-PEG-Acrylates
NPC-PEG-Acrylates
SAS-PEG-Acrylates
SC-PEG-Acrylates
SCM-PEG-Acrylates
SG-PEG-Acrylates
SS-PEG-Acrylates
SVA-PEG-Acrylates
 
2.固相吸附法制备PEG修饰蛋白
产品包括：
NH2-PEG-SH
NH2-PEG-Biotin
NH2-PEG-OPSS
NH2-PEG-OH
NH2-PEG-Hydrazide
NH2-PEG-Silane
NH2-peg-Acrylates
NH2-peg-Lipoicacid
NH2-peg-Acetylthio
NH2-PEG-NitrophenylCarbonates (NPC)
NH2-PEG-ValericAcids
NH2-PEG-Acrylamide
NH2-PEG-Bromide(Br)
NH2-PEG-Vinylsulfone(VS)
NH2-PEG-Methacrylate(MA)
NH2-PEG-Iodoacetate(IA)
NH2-PEG-Chloride
DBCO-PEG-NH2
TCO-PEG-NH2
Tetrazine-PEG-NH2
NH2-PEG-Folate
NH2-PEG-CHEMS
 
固相吸附法与液相吸附法的比较
产品包括：
Epoxides-PEG-COOH
ValericAcids-PEG-COOH
Acrylamide-PEG-COOH
Bromide-PEG-COOH
VS-PEG-COOH
Methacrylate-PEG-COOH
IA-PEG-COOH
Chloride-PEG-COOH
DBCO-PEG-COOH
TCO-PEG-COOH
Tetrazine-PEG-COOH
Folate-PEG-COOH
CHEMS-PEG-COOH
 
3.PEG醛制备单修饰的药用蛋白
产品包括：
OPSS-PEG-CHO
Hydrazide-PEG-CHO
Silane-peg-CHO
Acrylates-peg-CHO
Lipoicacid-peg-CHO
Tosylate-peg-CHO
Acetylthio-peg-CHO
NPC-PEG-CHO
SAS-PEG-CHO
SC-PEG-CHO
SCM-PEG-CHO
SG-PEG-CHO
SS-PEG-CHO
SVA-PEG-CHO
Epoxides-PEG-CHO
Valeric Acids-PEG-CHO
Acrylamide-PEG-CHO
Bromide-PEG-CHO
VS-PEG-CHO
Methacrylate-PEG-CHO
IA-PEG-CHO
Chloride-PEG-CHO
DBCO-PEG-CHO
TCO-PEG-CHO
Tetrazine-PEG-CHO
Folate-PEG-CHO
CHEMS-PEG-CHO
 
粒细胞集落刺激因子 (G-CSF)
产品列表：
Hydrazide-PEG-OPSS
Silane-peg-OPSS
Acrylates-peg-OPSS
Lipoicacid-peg-OPSS
Tosylate-peg-OPSS
Acetylthio-peg-OPSS
Aminooxy-PEG-OPSS
NPC-PEG-OPSS
SAS-PEG-OPSS
SC-PEG-OPSS
SCM-PEG-OPSS
SG-PEG-OPSS
SS-PEG-OPSS
SVA-PEG-OPSS
Epoxides-PEG-OPSS
ValericAcids-PEG-OPSS
Acrylamide-PEG-OPSS
Bromide-PEG-OPSS
VS-PEG-OPSS
Methacrylate-PEG-OPSS
IA-PEG-OPSS
Chloride-PEG-OPSS
DBCO-PEG-OPSS
TCO-PEG-OPSS
Tetrazine-PEG-OPSS
Folate-PEG-OPSS
CHEMS-PEG-OPSS
 
三批PEG30-rhG-CSF产品的制备
产品：
COOH-PEG-OH
MAL-PEG-OH
NHS-PEG-OH
N3-PEG-OH
Alkyne-PEG-OH
HS-PEG-OH
Biotin-PEG-OH
CHO-PEG-OH
OPSS-PEG-OH
Hydrazide-PEG-OH
Silane-peg-OH
Acrylates-peg-OH
Lipoicacid-peg-OH
Tosylate-peg-OH
Acetylthio-peg-OH
Aminooxy-PEG-OH
NPC-PEG-OH
SAS-PEG-OH
SC-PEG-OH
SCM-PEG-OH
SG-PEG-OH
SS-PEG-OH
SVA-PEG-OH
Epoxides-PEG-OH
ValericAcids-PEG-OH
Acrylamide-PEG-OH
Bromide-PEG-OH
VS-PEG-OH
Methacrylate-PEG-OH
IA-PEG-OH
Chloride-PEG-OH
DBCO-PEG-OH
TCO-PEG-OH
Tetrazine-PEG-OH
Folate-PEG-OH
CHEMS-PEG-OH
 
修饰和剂型化产品质量达到国际先进水平
产品：
Silane-peg-Hydrazide
Acrylates-peg-Hydrazide
Lipoicacid-peg-Hydrazide
Tosylate-peg-Hydrazide
Acetylthio-peg-Hydrazide
Aminooxy-PEG-Hydrazide
NPC-PEG-Hydrazide
SAS-PEG-Hydrazide
SC-PEG-Hydrazide
SCM-PEG-Hydrazide
SG-PEG-Hydrazide
SS-PEG-Hydrazide
SVA-PEG-Hydrazide
Epoxides-PEG-Hydrazide
ValericAcids-PEG-Hydrazide
Acrylamide-PEG-Hydrazide
Bromide-PEG-Hydrazide
VS-PEG-Hydrazide
Methacrylate-PEG-Hydrazide
IA-PEG-Hydrazide
Chloride-PEG-Hydrazide
DBCO-PEG-Hydrazide
TCO-PEG-Hydrazide
Tetrazine-PEG-Hydrazide
Folate-PEG-Hydrazide
CHEMS-PEG-Hydrazide
 
引入巯基的方法制备PEG修饰蛋白
产品列表：
Tosylate-peg-Lipoicacid
Acetylthio-peg-Lipoic acid
Aminooxy-PEG-Lipoicacid
NPC-PEG-Lipoic acid
SAS-PEG Lipoic acid
SC-PEG-Lipoic acid
SCM-PEG-Lipoic acid
SG-PEG-Lipoic acid
SS-PEG-Lipoicacid
SVA-PEG-Lipoicacid
Epoxides-PEG-Lipoicacid
ValericAcids-PEG-Lipoic acid
Acrylamide-PEG-Lipoicacid
Bromide-PEG-Lipoicacid
VS-PEG-Lipoicacid
Methacrylate-PEG-Lipoicacid
IA-PEG-Lipoicacid
Chloride-PEG-Lipoicacid
DBCO-PEG-Lipoicacid
TCO-PEG-Lipoicacid
Tetrazine-PEG-Lipoicacid
Folate-PEG-Lipoic acid
CHEMS-PEG-Lipoic acid