L-Homopropargylglycine
L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety that can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or &lduo;click &rduo; reaction between an azide and an alkyne or cyclooctyne. The alkyne-modified protein is detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and patible with downstream LC-MS⁄MS and MALDI MS analysis.
Molecular weight
163.60 (HCl salt)
Chemical position
C6H10ClNO2
CAS
98891-36-2
Solubility
Water, DMSO, DMF
Purity
>95% (H NMR)
Appearance
White crystalline
Storage conditions
-20C
Shipping conditions
Ambient temperature
L-Homopropargylglycine,HPG,炔标记蛋氨酸
公司：西安NG体育科技有限公司
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