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DBCO NHS ester Cat. # Quantity Price 34720 10mg 840.00 44720 25mg 1330.00 54720 50mg 2030.00 64720 100mg 3360.00 94720 1000mg 16660.00 Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain promoted alkyne azide cycloaddition (spAAC) – a copper free Click chemistry reaction. This is an amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine. DBCO reacts instantly with azides. The rate of the reaction is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines - this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines. General properties Appearance:                                                      off white solid Mass spec M+ increment:                                 315.1 Molecular weight:                                               430.45 Molecular formula:                                             C25H22N2O5 IUPAC name:                                                     6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide Solubility:                                                            good in DCM, DMF, DMSO Quality control:                                                   NMR 1H, HPLC-MS (95%) Storage conditions:Storage:                           12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.